Thursday | March 12, 2026 | 3:00 pm PST

Mitochondria and Power Generation, and Pollution Control of Impure Oxidants

 A recent review of critical factors identified neuroplasticity is the largest factor in human longevity, by a factor of 17(!). A central question, then is to understand the factors influencing neuroplasticity. At the heart of living processes lies energy creation. In the cell, oxidative phosphorylation as provided by oxidation of carbon in the mitochondria provides the vast majority of energy. This immense power is underestimated: It is 50% more efficient than that of nuclear power, 100% more efficient than classical combustion. However, as in all energy generating processes, it is impure, creating highly detrimental oxidants, which then drive central aging processes.
Coupling energy creation, and its control, heavily impact neuroplasticity. This lecture is a brief overview of oxidative phosphorylation, its consequent pollutants, and then those interventions which impact its efficiency. Ultimately, these results, and available data will be presented, which are demonstrated in changes in EEG.

About James:

Peter James Seberger, MD is a primary care, integrative, and preventive medicine doctor. He obtained both Ph.D. and M.D. from the University of Nebraska Medical Center, completing a Ph.D. in biochemistry and molecular biology in 1999 and his M.D. in 2003. He then moved and finished his residency in Family Medicine in 2003 in Wichita, KS. He has practiced primarily emergency medicine for the last 10 years, but opened a direct care practice in 2012.

Dr. Seberger works with his wife, Veronica, RN, BSN, BCN at Cognitive Performance & Health. He has a family medicine practice where he employs many types of modalities: medicine, vitamin supplementation, and neurofeedback. He says,  “I try to have as many tools in my tool box as I can. Sometimes patients are maxed out on medicines and they need additional means to control their blood pressure and get their glucose down.”

“I try to identify the primary reason for the problem–and address it. My goal is to have the patient well and balanced and stop any decline that may be occurring. And then, improve on their health, to really make them feel better and perform better.”